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Phenylbutyrate Na

Name: Phenylbutyrate Na
Brand: antibodies-online
SKU: ABIN7233276
Price: 121.54 EUR
Availability: InStock

Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

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N° du produit ABIN7233276

Fiche de données

Application

Inhibition (Inh)

Fonction

HDAC inhibitor

Attributs du produit

Chemical chaperone for misfolded proteins. Resolves ER stress in neuronal cells by aiding protein folding in the ER. Counteracts impaired glucose homeostasis in a mouse model of type 2 diabetes by preventing islet amyloid formation. Attenuates atherosclerotic progression and stabilizes existing plaques in mouse model of atherosclerosis via inhibition of ER stress. Protects against amyloid β-induced neurotoxicity in a mouse model. Weak histone deacetylase (HDAC) inhibitor which inhibits glioma cell proliferation. Active in vivo.

Pureté

>98 %

Chemical Name

4-Phenylbutyric acid, sodium salt

Formula

C10H11O2 • Na

Solubility

Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml).
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Radicicol
Inh 12772-57-5

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Daminozide
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Restrictions

For Research Use only
Format

Powder

Stock

RT
Sujet

4-PB, PBNa,Proliferation,Epigenetics,Posttranslational modification,Cell migration,Protein deacetylase,ER/Golgi,Cellular stress,Cell death,Stem cells,Atherosclerosis,Diabetes,Apoptosis inducer,Neurodegeneration,Chromatin

Poids moléculaire

186.2

Numéro CAS

1716-12-7