Lapin IgG Isotype Control
Aperçu rapide pour Lapin IgG Isotype Control (ABIN1045104)
Antigène
Type d'anticorp
Fragment
Application
Isotype
-
-
Hôte
- Lapin
-
Purification
- Rabbit serum IgG
-
Pureté
- > 95 % by SDS-PAGE
-
-
Hamster IgG isotype control
ELISA, WB, IHC, SDS IgG unconjugated
Rabbit IgG isotype controlELISA, WB, IHC, SDS IgG unconjugated
Rabbit IgG isotype control (Atto 550)FACS, IHC Polyclonal IgG Atto 550
Rabbit IgG isotype controlFACS, IHC, IP Polyclonal IgG unconjugated
Mouse IgG isotype controlFACS, ELISA Polyclonal IgG unconjugated
Goat IgG isotype controlFACS, ELISA Polyclonal IgG unconjugated
Rabbit IgG isotype controlFACS, ELISA Polyclonal IgG unconjugated
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Commentaires
-
Full length native Rabbit IgG Fc fragment
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS pH 7.4
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- -20 °C
-
-
- IgG
-
Classe de substances
- Antibody
-
Sujet
- The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody's two heavy chains, IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2-4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and alpha-2,6 linked sialic acid residues. The other part of an antibody, called the Fab region, contains variable sections that define the specific target that the antibody can bind. By contrast, the Fc region of all antibodies in a class are the same for each species, they are constant rather than variable.
Antigène
-
