ITK Produits
(IL2-Inducible T-Cell Kinase (ITK))
Catégories
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008].
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Catégories ITK en vedette
ITK Anticorps
High quality antibodies with extensive validation data.
ITK Kits ELISA
Reliable ELISA kits for a wide range of species.
ITK Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ITK recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, ICC, FACS
Validations
- (2)
- (5)
N° du produit
ABIN969222
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS, IF
Validations
- (6)
N° du produit
ABIN1589997
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
N° du produit
ABIN184605
Quantité
100 μg
Fiche technique
Fiche technique
ITK recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956705
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4886150
Quantité
96 tests
Fiche technique
Fiche technique
ITK recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5570598
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123402
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308231
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ITK
: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." dans: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." dans: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).
: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." dans: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).
: "Itk phosphorylation sites are required for functional activity in primary T cells." dans: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37112-21, (2003) (PubMed).
: "Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 4, pp. 1899-904, (2002) (PubMed).
: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." dans: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).
: "Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity." dans: Protein expression and purification, Vol. 22, Issue 2, pp. 211-9, (2001) (PubMed).
: "Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6435-41, (2000) (PubMed).
: "Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade." dans: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2219-30, (2000) (PubMed).
: "Rapid movements of vimentin on microtubule tracks: kinesin-dependent assembly of intermediate filament networks." dans: The Journal of cell biology, Vol. 143, Issue 1, pp. 159-70, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à ITK
IL2 inducible T cell kinase (Itk), IL2 inducible T-cell kinase (ITK), IL2-inducible T-cell kinase (Itk), Emt, EMT, LPFS1, LYK, PSCTK2, Tcsk, TskProtein level used designations for ITK
- T-cell-specific kinase
- interleukin-2-inducible T cell kinase
- kinase TLK
- tyrosine-protein kinase ITK/TSK
- IL-2-inducible T cell kinase
- IL-2-inducible T-cell kinase
- homolog of mouse T-cell itk/tsk
- interleukin-2-inducible T-cell kinase
- kinase EMT
- tyrosine-protein kinase LYK
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