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JMY Protéines

(Junction Mediating and Regulatory Protein, P53 Cofactor (JMY))

Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics.

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JMY Protein (AA 1-983) (His tag)

custom-made JMY Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Jmy Protein, UniprotID Q9QXM1

3 images

N° du produit ABIN7565150

Détails

JMY Protein (AA 1-988) (His tag)

custom-made JMY Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant JMY Protein, UniprotID Q8N9B5

3 images

N° du produit ABIN7554254

Détails

JMY Protein (AA 163-341) (His-IF2DI Tag)

JMY Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

Western Blotting (WB) image for Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 163-341) protein (His-IF2DI Tag) (ABIN7123654)

1 image

N° du produit ABIN7123654

Détails

JMY Protein (AA 1-983) (Strep Tag)

custom-made JMY Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3137379

Détails

JMY Protein (AA 1-988) (Strep Tag)

custom-made JMY Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3093298