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KCNU1 Produits

(Potassium Channel, Subfamily U, Member 1 (KCNU1))
Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+) (By similarity).

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Catégories KCNU1 en vedette

KCNU1 Anticorps

High quality antibodies with extensive validation data.

KCNU1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KCNU1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
N° du produit ABIN7245455
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN7269471
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB
Validations
  • (1)
N° du produit ABIN6293996
Quantité 50 μL
Fiche technique Fiche technique

KCNU1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093421
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3131831
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3109066
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits KCNU1

Zeng, Yang, Xia, Liu, Lingle: "SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 8, pp. 2599-604, (2015) (PubMed).

Zeng, Yang, Kim, Lingle, Xia: "Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 14, pp. 5879-84, (2011) (PubMed).

Yang, Zeng, Zhou, Xia, Lingle: "LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 48, pp. 19419-24, (2011) (PubMed).

Santi, Martínez-López, de la Vega-Beltrán, Butler, Alisio, Darszon, Salkoff: "The SLO3 sperm-specific potassium channel plays a vital role in male fertility." dans: FEBS letters, Vol. 584, Issue 5, pp. 1041-6, (2010) (PubMed).

Martínez-López, Santi, Treviño, Ocampo-Gutiérrez, Acevedo, Alisio, Salkoff, Darszon: "Mouse sperm K+ currents stimulated by pH and cAMP possibly coded by Slo3 channels." dans: Biochemical and biophysical research communications, Vol. 381, Issue 2, pp. 204-9, (2009) (PubMed).

Wang, Liu, Cho, Ren: "A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein." dans: Biology of reproduction, Vol. 81, Issue 3, pp. 539-44, (2009) (PubMed).

Yang, Zeng, Xia, Lingle: "Interactions between beta subunits of the KCNMB family and Slo3: beta4 selectively modulates Slo3 expression and function." dans: PLoS ONE, Vol. 4, Issue 7, pp. e6135, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à KCNU1

potassium channel, subfamily U, member 1 (Kcnu1), potassium calcium-activated channel subfamily U member 1 (KCNU1), KCa5, KCa5.1, Kcnma3, KCNMC1, mSlo3, Slo3

Protein level used designations for KCNU1

  • KSper
  • calcium-activated potassium channel subunit alpha-3
  • calcium-activated potassium channel, subfamily M subunit alpha-3
  • pH-sensitive maxi potassium channel
  • pore-forming subunit of the sperm-specific alkalization activated K(+) current
  • potassium channel subfamily U member 1
  • potassium large conductance pH-sensitive channel, subfamily M, alpha member 3
  • slowpoke homolog 3
  • Calcium-activated potassium channel subunit alpha-3
  • Calcium-activated potassium channel, subfamily M subunit alpha-3
  • Slowpoke homolog 3
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