KIR3DL1 Produits
(Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
Catégories
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
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Catégories KIR3DL1 en vedette
KIR3DL1 Anticorps
High quality antibodies with extensive validation data.
KIR3DL1 Kits ELISA
Reliable ELISA kits for a wide range of species.
KIR3DL1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (5)
N° du produit
ABIN5611325
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7157524
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
N° du produit
ABIN5611327
Quantité
0.1 mg
Fiche technique
Fiche technique
KIR3DL1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957298
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4883509
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6385893
Quantité
96 tests
Fiche technique
Fiche technique
KIR3DL1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123687
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308699
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3082636
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits KIR3DL1
: "Clinical impact of NK-cell reconstitution after reduced intensity conditioned unrelated cord blood transplantation in patients with acute myeloid leukemia: analysis of a prospective phase II ..." dans: Bone marrow transplantation, Vol. 52, Issue 10, pp. 1428-1435, (2017) (PubMed).: "Immunoelectron microscopic observation of the subcellular localization of kisspeptin, neurokinin B and dynorphin A in KNDy neurons in the arcuate nucleus of the female rat." dans: Neuroscience letters, Vol. 612, pp. 161-6, (2016) (PubMed).
: "The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events." dans: PLoS pathogens, Vol. 11, Issue 12, pp. e1005286, (2015) (PubMed).
: "Neurokinin B- and kisspeptin-positive fibers as well as tuberoinfundibular dopaminergic neurons directly innervate periventricular hypophyseal dopaminergic neurons in rats and mice." dans: Neuroscience research, Vol. 84, pp. 10-8, (2014) (PubMed).
: "Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 1, pp. 503-11, (2013) (PubMed).
: "CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients." dans: European journal of immunology, Vol. 42, Issue 2, pp. 447-57, (2012) (PubMed).
: "Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells." dans: PLoS ONE, Vol. 7, Issue 1, pp. e30264, (2012) (PubMed).
: "NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human." dans: The Journal of clinical investigation, Vol. 121, Issue 4, pp. 1456-70, (2011) (PubMed).
: "Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 1, pp. 62-72, (2010) (PubMed).
: "NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs." dans: PLoS ONE, Vol. 5, Issue 8, pp. e11966, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à KIR3DL1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (KIR3DL1), uncharacterized LOC100437736 (LOC100437736), killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 (KIR3DL1), killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (Kir3dl1), CD158E1, KIR, KIR3DL1, KIR3DL1/S1, KIR3DL3, Kirl1, Kirl2, Krl1, NKAT3, NKB1, NKB1BProtein level used designations for KIR3DL1
- killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
- killer immunoglobulin-like receptor KIR3DL-like 1
- killer cell immunoglobulin-like receptor variant 001
- killer cell immunoglobulin-like receptor KIR3DL1-like 1
- killer cell immunoglobulin-like receptor 3DL1-like
- CD158 antigen-like family member E
- HLA-BW4-specific inhibitory NK cell receptor
- KIR antigen 3DL1
- MHC class I NK cell receptor
- NK-receptor
- NKAT-3
- killer Ig receptor
- killer cell immunoglobulin-like receptor 3DL1
- natural killer-associated transcript 3
- p70 NK receptor CL-2/CL-11
- p70 killer cell inhibitory receptor
- p70 natural killer cell receptor clones CL-2/CL-11
- KIR-like receptor 1
- killer cell immunoglobulin-like receptor Kir3dl1
- killer immunoglobulin receptor-like protein 1
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