Ferritin Kit ELISA

N° du produit ABIN1326844

Détail du produit Ferritin Kit ELISA

Antigène: Ferritin (FE)

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: The Ferritin blood test is a solid phase direct sandwich ELISA method. The samples and diluted anti-Ferritin-HRP conjugate are added to the wells coated with Mab to Ferritin. Ferritin in the patient's serum binds to anti-Ferritin MAb on the wells. Unbound protein is washed off by wash buffer. The anti-ferritin-HRP conjugated detection antibody is added and then binds to ferritin. Unbound HRP conjugate is washed off by wash buffer. Upon the addition of the substrate, the intensity of color is proportional to the concentration of Ferritin in the samples. A standard curve is prepared relating color intensity to the concentration of the Ferritin.

Type d'échantillon: Blood, Serum

Analytical Method: Quantitative

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour Ferritin Kit ELISA (ABIN1326844)

Khambalia, Collins, Roberts, Morris, Powell, Tasevski, Nassar: "High maternal serum ferritin in early pregnancy and risk of spontaneous preterm birth." dans: The British journal of nutrition, pp. 1-7, (2015) (PubMed).

Winner, Sharkey-Toppen, Zhang, Pennell, Simonetti, Zweier, Vaccaro, Raman: "Iron and noncontrast magnetic resonance T2* as a marker of intraplaque iron in human atherosclerosis." dans: Journal of vascular surgery, Vol. 61, Issue 6, pp. 1556-64, (2015) (PubMed).

Détail du antigène

Antigène: Ferritin (FE)

Autre désignation: Ferritin (FE Produits)

Synonymes: 1HCH Kit ELISA, BEST:LD36673 Kit ELISA, CG2216 Kit ELISA, Dmel\\CG2216 Kit ELISA, FER1 Kit ELISA, FER1HCH Kit ELISA, Fer-L Kit ELISA, Fer1 Kit ELISA, Fer1HC Kit ELISA, FerHCH Kit ELISA, HCH Kit ELISA, T21 Kit ELISA, T9 Kit ELISA, fer1 Kit ELISA, fer1hch Kit ELISA, l(3)00451 Kit ELISA, l(3)j10B4 Kit ELISA, SFerH-1 Kit ELISA, SOF-35 Kit ELISA, SOF-5L Kit ELISA, NV13011 Kit ELISA, ACP1 Kit ELISA, F8A5.24 Kit ELISA, F8A5_24 Kit ELISA, Ferritin 1 heavy chain homologue Kit ELISA, ferritin light chain Kit ELISA, ferritin Kit ELISA, chromosome 26 open reading frame, human C10orf131 Kit ELISA, hyaluronan and proteoglycan link protein 2 Kit ELISA, NAD(P)-linked oxidoreductase superfamily protein Kit ELISA, Fer1HCH Kit ELISA, H-1 Kit ELISA, YPDSF_1340 Kit ELISA, ftnA Kit ELISA, Ft Kit ELISA, C26H10orf131 Kit ELISA, HAPLN2 Kit ELISA, AT1G60730 Kit ELISA

Sujet: Human Ferritin has a molecular weight of approximately 450,000 Daltons, and consists of a protein shell around an iron core each molecule of Ferritin may contain as many as 4,000 iron atoms. Under normal conditions, this may represent 25% of the Total iron found in the body. In addition, Ferrritin can be found in several isomers. High concentrations of Ferritin are found in the cytoplasm of the reticuloendothelial system, the liver, spleen and bone marrow. Methods previously used to measure iron in such tissues are invasive, cause patient trauma and lack adequate sensitivity. The measurement of Ferritin in serum through a Ferritin Blood Test is useful in determining changes in body iron storage, and is non-invasive with relatively little patient discomfort. Serum Ferritin levels can be measured routinely with a Ferritin test and are particularly useful in the early detection of iron-deficiency anemia in apparently healthy people. Serum Ferritin measurements are also clinically significant in the monitoring of the iron status of pregnant women, blood donors, and renal dialysis patients. High Ferritin levels may indicate iron overload without apparent liver damage, as may be noted in the early stages of idiopathic hemochromatosis. Ferritin levels in serum have also been used to evaluate clinical conditions not related to iron storage, including inflammation, chronic liver disease, and malignancy.

Pathways: Transition Metal Ion Homeostasis