APP Kit ELISA

N° du produit ABIN2042350

Détail du produit APP Kit ELISA

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 2-20000 pg/mL

Seuil minimal de détection: 2 pg/mL

Application: ELISA

Marque: BioAssay™

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 10 pg/mL

Ingrédients: 96-well plate pre-coated with anti-APP, Human
Lyophilized recombinant APP, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Human APP in cell culture supernates, serum and plasma (heparin, EDTA).Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid (A ), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive.

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Autre désignation: APP (APP Produits)

Synonymes: AAA Kit ELISA, ABETA Kit ELISA, ABPP Kit ELISA, AD1 Kit ELISA, APPI Kit ELISA, CTFgamma Kit ELISA, CVAP Kit ELISA, PN-II Kit ELISA, PN2 Kit ELISA, aaa Kit ELISA, abeta Kit ELISA, abpp Kit ELISA, ad1 Kit ELISA, appi Kit ELISA, ctfgamma Kit ELISA, cvap Kit ELISA, pn2 Kit ELISA, APP Kit ELISA, APP-like Kit ELISA, APPL Kit ELISA, Abeta Kit ELISA, BcDNA:GH04413 Kit ELISA, CG7727 Kit ELISA, Dmel\\CG7727 Kit ELISA, EG:65F1.5 Kit ELISA, appl Kit ELISA, Abpp Kit ELISA, Adap Kit ELISA, Ag Kit ELISA, Cvap Kit ELISA, E030013M08Rik Kit ELISA, betaApp Kit ELISA, app Kit ELISA, wu:fj34d10 Kit ELISA, wu:fk65e12 Kit ELISA, zgc:85740 Kit ELISA, amyloid beta precursor protein Kit ELISA, amyloid beta (A4) precursor protein Kit ELISA, beta amyloid protein precursor-like Kit ELISA, amyloid beta (A4) precursor protein a Kit ELISA, amyloid beta precursor protein L homeolog Kit ELISA, APP Kit ELISA, app Kit ELISA, Appl Kit ELISA, App Kit ELISA, appa Kit ELISA, app.L Kit ELISA

ID gène: 351

UniProt: P05067

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour