BMP4 Kit ELISA

N° du produit ABIN2042363

Détail du produit BMP4 Kit ELISA

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 62.5-4000 pg/mL

Seuil minimal de détection: 62.5 pg/mL

Application: ELISA

Marque: BioAssay™

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 4 pg/mL

Ingrédients: 96-well plate pre-coated with anti-BMP-4, Human
Lyophilized recombinant BMP-4, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Human BMP-4 in bone tissue and cell culture supernates.Bone morphogenetic protein 4 is a protein that in humans is encoded by the BMP4 gene which is located to 14q22-q23.1, 2 The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. BMP4 is a polypeptide belonging to the TGF- superfamily of proteins. It, like other bone morphogenetic proteins, is involved in bone and cartilage development, specifically tooth and limb development and fracture repair. It has been shown to be involved in muscle development, bone mineralization, and uteric bud development. BMP4 has also been implicated in Fibrodysplasia Ossificans Progressiva in which it is underexpressed. In human embryonic development, BMP4 is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog (released from the ventral portion of the notochord) to establish a dorsal-ventral axis for the differentiation of later structures. BMP4 stimulates differentiation of overlying ectodermal tissue. Inhibition of the BMP4 signal (by chordin, noggin, or follistatin) causes the ectoderm to differentiate into the neural plate. The standard product used in this kit is recombinant BMP-4 with the molecular mass of 26kD.

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Autre désignation: BMP-4 (BMP4 Produits)

Synonymes: BMP2B Kit ELISA, BMP2B1 Kit ELISA, MCOPS6 Kit ELISA, OFC11 Kit ELISA, ZYME Kit ELISA, Bmp-4 Kit ELISA, Bmp2b Kit ELISA, Bmp2b-1 Kit ELISA, Bmp2b1 Kit ELISA, BOMPR4A Kit ELISA, bmp-4 Kit ELISA, zbmp-4 Kit ELISA, zgc:100779 Kit ELISA, BMP-4 Kit ELISA, XBMP-4 Kit ELISA, bmp2b Kit ELISA, bmp2b1 Kit ELISA, bmp4 Kit ELISA, ofc11 Kit ELISA, xbmp4 Kit ELISA, zyme Kit ELISA, BMP4 Kit ELISA, bone morphogenetic protein 4 Kit ELISA, bone morphogenetic protein 4 L homeolog Kit ELISA, bone morphogenetic protein 4 S homeolog Kit ELISA, BMP4 Kit ELISA, Bmp4 Kit ELISA, bmp4 Kit ELISA, bmp4.L Kit ELISA, bmp4.S Kit ELISA

ID gène: 652

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development