Endoglin Kit ELISA
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- Antigène Voir toutes Endoglin (ENG) Kits ELISA
- Endoglin (ENG)
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 6-10000 pg/mL
- Seuil minimal de détection
- 6 pg/mL
- Application
- ELISA
- Marque
- BioAssay™
- Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Sensibilité
- < 15 pg/mL
- Ingrédients
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96-well plate pre-coated with anti-CD105, Human
Lyophilized recombinant CD105, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL - Featured
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- Discover our top product ENG Kit ELISA
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- Plaque
- Pre-coated
- Protocole
- Sandwich ELISA quantitative detection kit for Human CD105 in cell culture supernates, serum and plasma (heparin, EDTA).CD105, also called Endoglin, is a homodimeric membrane glycoprotein primarily associated with human vascular endothelium. It is also found on bone marrow proerythroblasts, activated monocytes, and lymphoblasts in childhood leukemia. Endoglin is a component of the transforming growth factor-beta (TGFB) receptor complex and binds TGFB1 with high affinity.1 CD105 gene is mapped to 9q34.1. The coding region of the gene contains 14 exons.2 The protein consists of a homodimer of 180kDA with disulfide links. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. Furthermore, it also has a role in the balance of ALK1 and ALK5 signaling to regulate endothelial cell proliferation.3 Moreover, the elevated expression of endoglin in the surgically excised CNVMs suggested a persisting postmitotic activation in an advanced stage of neovascular tissue.4 The standard product used in this kit is extracellular part of recombinant human CD105, from E26 to G586. As a result of glycosylation, the molecular mass is 75-85kD.
- Restrictions
- For Research Use only
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- Stock
- 4 °C/-20 °C
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- Antigène Voir toutes Endoglin (ENG) Kits ELISA
- Endoglin (ENG)
- Autre désignation
- CD105 (ENG Produits)
- Synonymes
- ENG Kit ELISA, MGC137842 Kit ELISA, DKFZp469D0419 Kit ELISA, END Kit ELISA, HHT1 Kit ELISA, ORW1 Kit ELISA, AI528660 Kit ELISA, AI662476 Kit ELISA, CD105 Kit ELISA, S-endoglin Kit ELISA, endoglin Kit ELISA, ENG Kit ELISA, Eng Kit ELISA
- ID gène
- 2022
- UniProt
- P17813
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