Granulin Kit ELISA

N° du produit ABIN2042639

Détail du produit Granulin Kit ELISA

Antigène: Granulin (GRN)

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 1.6-100 ng/mL

Seuil minimal de détection: 1.6 ng/mL

Application: ELISA

Marque: BioAssay™

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 50 pg/mL

Ingrédients: 96-well plate pre-coated with anti-Progranulin, Human
Lyophilized recombinant Progranulin, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Human Progranulin in cell culture supernates, serum, plasma (heparin, EDTA), saliva and urine.Granulin, also known as Proepithelin (PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88kD precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6kD peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: Granulin (GRN)

Autre désignation: Progranulin (GRN Produits)

Synonymes: GRN Kit ELISA, grn Kit ELISA, wu:fb11g12 Kit ELISA, wu:fj18f05 Kit ELISA, MGC53354 Kit ELISA, DKFZp459H066 Kit ELISA, CLN11 Kit ELISA, GEP Kit ELISA, GP88 Kit ELISA, PCDGF Kit ELISA, PEPI Kit ELISA, PGRN Kit ELISA, epithelin Kit ELISA, acrogranin Kit ELISA, granulin precursor Kit ELISA, granulin a Kit ELISA, Granulins Kit ELISA, granulin L homeolog Kit ELISA, granulin Kit ELISA, GRN Kit ELISA, grna Kit ELISA, grn Kit ELISA, grn.L Kit ELISA, granulin Kit ELISA, ORF1 granulin Kit ELISA, Grn Kit ELISA

Classe de substances: Viral Protein

ID gène: 2896

UniProt: P28799