CD27 Kit ELISA
Aperçu rapide pour CD27 Kit ELISA (ABIN2042699)
Antigène
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Méthode de détection
Type de méthode
Gamme de detection
Application
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Seuil minimal de détection
- 62.5 pg/mL
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Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensibilité
- < 10 pg/mL
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Ingrédients
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96-well plate pre-coated with anti-TNFRSF7/CD27, Mouse
Lyophilized recombinant TNFRSF7/CD27, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plaque
- Pre-coated
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Protocole
- Sandwich ELISA quantitative detection kit for Mouse TNFRSF7/CD27 in cell culture supernates and serum.CD27 antigen, also called CD27 or TNFRSF7 is a tumor necrosis factor receptor. This gene is mapped to 12p13.31. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
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Restrictions
- For Research Use only
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Stock
- 4 °C/-20 °C
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- CD27 (CD27 Molecule (CD27))
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Autre désignation
- TNFRSF7/CD27
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ID gène
- 21940
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UniProt
- P41272
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Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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