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PLAU Kit ELISA

Ce kit ELISA Humain PLAU est un kit ELISA Colorimetric conçu pour quantifier Humain PLAU.
N° du produit ABIN2042715

Aperçu rapide pour PLAU Kit ELISA (ABIN2042715)

Antigène

Voir toutes PLAU Kits ELISA
PLAU (Plasminogen Activator, Urokinase (PLAU))

Reactivité

  • 12
  • 5
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  • 3
  • 3
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  • 2
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Humain

Méthode de détection

Colorimetric

Type de méthode

Sandwich ELISA

Gamme de detection

62.5-4000 pg/mL

Application

ELISA
  • Seuil minimal de détection

    62.5 pg/mL

    Réactivité croisée (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensibilité

    < 5 pg/mL

    Ingrédients

    96-well plate pre-coated with anti-uPA/PLAU, Human
    Lyophilized recombinant uPA/PLAU, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plaque

    Pre-coated

    Protocole

    Sandwich ELISA quantitative detection kit for Human uPA/PLAU in cell culture supernates, serum and plasma (heparin, EDTA).Plasminogen activator,urokinase (PLAU, uPA) converts plasminogen to plasmin. Plasmin is involved in processing of amyloid precursor protein and degrades secreted and aggregated amyloid-beta, a hallmark of Alzheimer disease (AD). Urokinase has a molecular mass of about 54kD and is composed of 2 disulfide-linked chains, A and B, of molecular masses 18kD and 33kD, respectively. It localized on 10q24. uPA facilitates cell migration by localizing proteolisys on the cell surface and by inducing intracellular signalling pathways. In human vascular smooth muscle cell (VSMC), uPA stimulates migration via the uPA receptor (uPAR) signalling complex containing TYK2 and phosphatidylinositol 3-kinase (PI3-K).

    Restrictions

    For Research Use only
  • Stock

    4 °C/-20 °C
  • Antigène Voir toutes PLAU Kits ELISA

    PLAU (Plasminogen Activator, Urokinase (PLAU))

    Autre désignation

    uPA/PLAU

    ID gène

    5328

    UniProt

    P00749

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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