Endothelin Big Kit ELISA

N° du produit ABIN2648509

Kit ELISA Endothelin Big Humain, Colorimetric test pour la quantification de Humain Endothelin Big.

Aperçu rapide pour Endothelin Big Kit ELISA (ABIN2648509)

Antigène: Endothelin Big

Reactivité: Humain

Méthode de détection: Colorimetric

Application: ELISA

Type d'échantillon: Serum, Plasma, Plasma (EDTA)

Détail du produit Endothelin Big Kit ELISA

Sensibilité: 0.02 pmol/L

Attributs du produit: Big Endothelin-1 (BigET) is a peptide of 38 amino acids and is the precursor of Endothelin-1 (ET), represented by amino acids 1-21 (http://www.uniprot.org/uniprot/P05305). ET is a potent vasoconstrictor and is produced by vascular endothelial cells. Accordingly it has a wide tissue distribution (http://www.ncbi.nlm.nih.gov/UniGene/ESTProfileViewer.cgi?uglist=Hs.511899). The cleavage of BigET by Endothelin Converting Enzyme (ECE) leads to ET and to a C-terminal fragment. Both BigET and ET are strong independent predictors of survival in patients with congestive heart failure, and identify a population with a very high risk mortality. The half-life of ET (1-21) in plasma is less than one minute, whereas clearance of BigET is much slower. BigET can therefore be determined more easily.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Volume d'échantillon: 50 μL

Durée du test: 5.5 h

Plaque: Pre-coated

Protocole: Human Big Endothelin-1 ELISA Assay Kit in serum & plasma. Big Endothelin-1 ELISA Assay Kit is manufactured by Biomedica Gruppe (www.bmgrp.com) and is for research use only, not to be used in diagnostic procedures.

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Détail du antigène

Antigène: Endothelin Big

Autre désignation: Big Endothelin