C-Peptide Kit ELISA
Aperçu rapide pour C-Peptide Kit ELISA (ABIN2648560)
Antigène
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Méthode de détection
Application
Type d'échantillon
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Specificité
- Ultrasensitive ELISA
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Sensibilité
- 0.57 pg/ml
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Attributs du produit
- C-peptide is a small 31-amino acid peptide usually produced in the beta cell of pancreas as a byproduct of the cleavage of proinsulin in the synthesis of insulin. Proinsulin consists of A and B chain and connecting peptide in the middle, called C-peptide. It is generally found in equimolar amounts equal to insulin in circulation. Since the half-life of C-peptide is 3-4 times that of insulin, it serves as a useful measure of insulin production in the beta cells of the pancreas. Testing for C-peptide levels can help find the cause of low blood sugar (hypoglycemia) aid in distinguishing type 1 from type 2 diabetes. A person with diabetes may have a normal level of C-peptide which indicates the body is making plenty of insulin but the body is just not responding properly to it. This is the hallmark of type 2 diabetes (adult insulin-resistant diabetes). For subjects with type 1 diabetes treated with insulin, measuring C-peptide level is useful in evaluating beta cell function related to synthesis and release endogenous insulin into the circulation. Some studies have suggested that C-peptide may have chemotactic effects on the inflammatory cells and might have a role in increased risk of atherosclerosis in persons with type-2 diabetes.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Volume d'échantillon
- 50 μL
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Durée du test
- 2.5 h
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Restrictions
- For Research Use only
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Stock
- 4 °C
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- C-Peptide
Antigène Voir toutes C-Peptide Kits ELISA
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