IL-32 alpha Kit ELISA

N° du produit ABIN4986954

Détail du produit IL-32 alpha Kit ELISA

Antigène: IL-32 alpha (IL32A) (Interleukin 32 alpha (IL32A))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 15.625-1000 pg/mL

Seuil minimal de détection: 15.625 pg/mL

Application: ELISA

Type d'échantillon: Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)

Analytical Method: Quantitative

Specificité: Natural and recombinant Human IL-32a Ligand

Sensibilité: 7 pg/mL

Matériel non inclus:

• Microplate reader.
• Pipettes and pipette tips.
• EP tube Deionized or distilled water.

Information d'application

Indications d'application: Detection Wavelength: 450 nm

Volume d'échantillon: 20 μL

Durée du test: 3 h

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Détail du antigène

Antigène: IL-32 alpha (IL32A) (Interleukin 32 alpha (IL32A))

Autre désignation: IL-32a (IL32A Produits)

Synonymes: IL-32alpha Kit ELISA, IL-32beta Kit ELISA, IL-32delta Kit ELISA, IL-32gamma Kit ELISA, NK4 Kit ELISA, TAIF Kit ELISA, TAIFa Kit ELISA, TAIFb Kit ELISA, TAIFc Kit ELISA, TAIFd Kit ELISA, interleukin 32 Kit ELISA, IL32 Kit ELISA

Sujet: IL-32α is the shortest and most abundant of four potential splice variants of the proinflammatory cytokine IL-32 (previously called NK4) with a predicted unmodified size of 15 kDa. Potential modifications include myristoylation and N-glycosylation. The IL-32α shows increased potency at inducing CXCL2/MIP-2 and CXCL8 expression in PBMC relative to uncleaved IL-32α. Transfected IL-32α was more likely to be cellassociated as compared to IL-32β, suggesting an intracellular function. IL-32 is induced by mitogens in peripheral lymphocytes, by IFNγ in epithelial cells, or by IL-12 with IL-18 in NK cells and in turn induces cytokine expression.