BMP2 Kit ELISA

N° du produit ABIN5510535

Kit ELISA Chien BMP2, test Colorimetric pour la quantification de Chien BMP2.

Aperçu rapide pour BMP2 Kit ELISA (ABIN5510535)

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Épitope: AA 283-396

Reactivité: Chien

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit BMP2 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Dog Canine BMP-2

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: CHO
Immunogen sequence: Q283-R396

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Autre désignation: Bmp2

Sujet:

Protein Function: Induces cartilage and bone formation.

Background: Bone morphogenetic protein-2(BMP-2, BMP 2A) belongs to the transforming growth factor beta(TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice. BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase(MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis. Bone morphogenic proteins(BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion. The standard product used in this kit is recombinant Dog Canine BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.

Synonyms: Bone morphogenetic protein 2,BMP-2,Bone morphogenetic protein 2A,BMP-2A,Bmp2,Bmp-2,

Full Gene Name: Bone morphogenetic protein 2

Cellular Localisation: Secreted.

UniProt: P21274

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation