LGALS1/Galectin 1 Kit ELISA

N° du produit ABIN5510585

Ce kit ELISA Humain LGALS1/Galectin 1 est un kit ELISA Colorimetric conçu pour quantifier Humain LGALS1/Galectin 1. Ce Kit ELISA a été cité dans 2+ publications.

Aperçu rapide pour LGALS1/Galectin 1 Kit ELISA (ABIN5510585)

Antigène: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Épitope: AA 2-135

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit LGALS1/Galectin 1 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Galectin-1

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: E.coli
Immunogen sequence: A2-D135

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Références pour LGALS1/Galectin 1 Kit ELISA (ABIN5510585)

You, Tan, Dai, Chen, Xu, Yang, Zhang, Bai, Bie: "MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma." dans: Oncotarget, Vol. 7, Issue 35, pp. 57099-57116, (2018) (PubMed).

Chong, Tang, Xiong, Jiang, Xu, Huang, Wang, Zhou, Shi, Wu, Wang: "Galectin-1 from cancer-associated fibroblasts induces epithelial-mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 175, (2017) (PubMed).

Détail du antigène

Antigène: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Autre désignation: LGALS1

Sujet:

Protein Function: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. .

Background: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Its expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. Additionally, Galectin-1 is thought to play a role in creating immune tolerance in pregnancy.

Synonyms: Galectin-1,Gal-1,14 kDa laminin-binding protein,HLBP14,14 kDa lectin,Beta-galactoside-binding lectin L-14-I,Galaptin,HBL,HPL,Lactose-binding lectin 1,Lectin galactoside-binding soluble 1,Putative MAPK-activating protein PM12,S-Lac lectin 1,LGALS1,

Full Gene Name: Galectin-1

Cellular Localisation: Secreted, extracellular space, extracellular matrix.

UniProt: P09382

Pathways: Carbohydrate Homeostasis