IL29 Kit ELISA
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- Antigène Voir toutes IL29 Kits ELISA
- IL29 (Interleukin 29 (IL29))
- Épitope
- AA 20-200
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Reactivité
- Chien
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Application
- ELISA
- Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Dog Caninea IL-29
- Marque
- PicoKine™
- Analytical Method
- Quantitative
- Specificité
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Expression system for standard: NSO
Immunogen sequence: G20-T200 - Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Attributs du produit
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Sequence similarities: Belongs to the lambda interferon family.
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- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Date de péremption
- 12 months
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- Antigène Voir toutes IL29 Kits ELISA
- IL29 (Interleukin 29 (IL29))
- Autre désignation
- IFNL1 (IL29 Produits)
- Sujet
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Protein Function: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Background: Interferon lambda-1, also called Interleukin-29(IL-29) is a protein that in Dog Canineas is encoded by the IL29 gene. IL-29 is a member of the helical cytokine family and is a type III interferon. This gene is mapped to 19q13.2. It is a cytokine with immunomodulatory activity. This gene may play a role in antiviral immunity. It can up-regulates MHC class I antigen expression. It is the ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses.
Synonyms: Interferon lambda-1,IFN-lambda-1,Cytokine Zcyto21,Interleukin-29,IL-29,IFNL1,IL29, ZCYTO21,
Full Gene Name: Interferon lambda-1
Cellular Localisation: Secreted. - UniProt
- Q8IU54
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