Sclerostin Kit ELISA
Aperçu rapide pour Sclerostin Kit ELISA (ABIN5510605)
Antigène
Voir toutes Sclerostin (SOST) Kits ELISAÉpitope
Reactivité
Méthode de détection
Type de méthode
Application
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Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Sclerostin/SOST
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Marque
- PicoKine™
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Analytical Method
- Quantitative
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Specificité
- Expression system for standard: NSO, Immunogen sequence: Q24-Y213
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Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Attributs du produit
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Tissue Specificity: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). .
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Sclerostin (SOST) ELISA Kit
SOST Reactivité: Humain Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Sclerostin (SOST) ELISA KitSOST Reactivité: Souris Colorimetric Sandwich ELISA 6.25 pg/mL - 400 pg/mL Plasma, Serum, Tissue Homogenate
Sclerostin (SOST) ELISA KitSOST Reactivité: Rat Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Sclerostin (SOST) ELISA KitSOST Reactivité: Rat Colorimetric Sandwich ELISA 31.25 pg/mL - 2000 pg/mL Cell Culture Supernatant, Plasma, Serum
Sclerostin (SOST) ELISA KitSOST Reactivité: Souris AA 24-211 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Sclerostin (SOST) ELISA KitSOST Reactivité: Rat AA 29-213 Colorimetric Sandwich ELISA
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Plaque
- Pre-coated
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Restrictions
- For Research Use only
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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Date de péremption
- 12 months
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- Sclerostin (SOST)
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Autre désignation
- SOST
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Sujet
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Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .
Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.
Synonyms: Sclerostin,SOST,UNQ2976/PRO7455/PRO7476,
Full Gene Name: Sclerostin
Cellular Localisation: Secreted, extracellular space, extracellular matrix. -
UniProt
- Q9BQB4
Antigène Voir toutes Sclerostin (SOST) Kits ELISA
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