TGFB2 Kit ELISA

N° du produit ABIN5510611

Ce kit ELISA Colorimetric est conçu pour la mesure quantitative de Singe TGFB2.

Aperçu rapide pour TGFB2 Kit ELISA (ABIN5510611)

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Épitope: AA 303-414

Reactivité: Singe

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit TGFB2 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated monkey primate TGF-beta 2

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: NSO
Immunogen sequence: A303-S414

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Sequence similarities: Belongs to the TGF-beta family.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Autre désignation: TGFB2

Sujet:

Protein Function: TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

Background: Transforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured monkey primate anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.

Synonyms: Transforming growth factor beta-2,TGF-beta-2,BSC-1 cell growth inhibitor,Cetermin,Glioblastoma-derived T-cell suppressor factor,G-TSF,Polyergin,Latency-associated peptide,LAP,TGFB2,

Full Gene Name: Transforming growth factor beta-2

Cellular Localisation: Secreted.

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus