CXCL14 Kit ELISA

N° du produit ABIN5510625

Kit ELISA Porc CXCL14, test Colorimetric pour la quantification de Porc CXCL14.

Aperçu rapide pour CXCL14 Kit ELISA (ABIN5510625)

Antigène: CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Épitope: AA 35-111

Reactivité: Porc

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit CXCL14 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Pig porcine CXCL14

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: E.coli
Immunogen sequence: S35-E111

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.

Tissue Specificity: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte- derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Autre désignation: CXCL14

Sujet:

Protein Function: Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. .

Background: Chemokine(C-X-C motif) ligand 14(CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK(for breast and kidney-expressed chemokine). This gene is mapped to 5q31.1. CXCL14 is constitutively expressed at high levels in many normal tissues, it has been found that fibroblasts are the primary source of CXCL14 and that CXCL14 is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. It is also a potent chemoattractant and activator of dendritic cells, is implicated in homing of these cells, and can stimulate the migration of activated NK cells. CXCL14 also inhibits angiogenesis, possibly as a result of its ability to block endothelial cell chemotaxis. In addition to it, CXCL14 is a potent chemokine for immature DCs, with a chemoattractive activity comparable to bacterial fMLP and MIP1A.

Synonyms: C-X-C motif chemokine 14,Chemokine BRAK,MIP-2G,Small-inducible cytokine B14,CXCL14,MIP2G, NJAC, SCYB14,PSEC0212, UNQ240/PRO273,

Full Gene Name: C-X-C motif chemokine 14

Cellular Localisation: Secreted.

UniProt: O95715

Pathways: Autophagy