FABP4 Kit ELISA
Aperçu rapide pour FABP4 Kit ELISA (ABIN5510643)
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Reactivité
Méthode de détection
Type de méthode
Application
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Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human FABP4
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Marque
- PicoKine™
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Analytical Method
- Quantitative
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Specificité
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Expression system for standard: E.coli
Immunogen sequence: M1-A132 -
Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Plaque
- Pre-coated
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Restrictions
- For Research Use only
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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Date de péremption
- 12 months
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- FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))
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Autre désignation
- FABP4
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Sujet
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Protein Function: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). .
Background: FABP4, also known as aP2 (adipocyte Protein 2), encodes the fatty acid binding protein found in adipocytes. The FABP4 gene is mapped to 8q21. FABP4 functions as a cytosolic lipid chaperone in macrophages and is involved in regulating macrophage endoplasmic reticulum (ER) stress. Aditionally, FABP4 protein is expressed in HBEs and is strongly upregulated by both IL4 and IL13 and downregulated by IFN-gamma, suggesting a role in allergic airway inflammation.
Synonyms: Fatty acid-binding protein, adipocyte,Adipocyte lipid-binding protein,ALBP,Adipocyte-type fatty acid-binding protein,A-FABP,AFABP,Fatty acid-binding protein 4,FABP4,
Full Gene Name: Fatty acid-binding protein, adipocyte
Cellular Localisation: Cytoplasm. Nucleus. Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity).. -
UniProt
- P15090
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Pathways
- Brown Fat Cell Differentiation
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