WFDC2 Kit ELISA

N° du produit ABIN5510648

Ce kit ELISA Humain WFDC2 est un kit ELISA Colorimetric conçu pour quantifier Humain WFDC2. Ce Kit ELISA a été cité dans 1 publication.

Aperçu rapide pour WFDC2 Kit ELISA (ABIN5510648)

Antigène: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Épitope: AA 31-124

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit WFDC2 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human HE4

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: E.coli
Immunogen sequence: E31-F124

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Références pour WFDC2 Kit ELISA (ABIN5510648)

Dong, Liu, Li: "Value of HE4 Combined with Cancer Antigen 125 in the Diagnosis of Endometrial Cancer." dans: Pakistan journal of medical sciences, Vol. 33, Issue 4, pp. 1013-1017, (2017) (PubMed).

Détail du antigène

Antigène: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Autre désignation: WFDC2

Sujet:

Protein Function: Broad range protease inhibitor. .

Background: WAP four-disulfide core domain protein 2, also known as Human Epididymis Protein 4 (HE4), is a protein that in humans is encoded by the WFDC2 gene. This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

Synonyms: WAP four-disulfide core domain protein 2,Epididymal secretory protein E4,Major epididymis-specific protein E4,Putative protease inhibitor WAP5,WFDC2,HE4, WAP5,

Full Gene Name: WAP four-disulfide core domain protein 2

Cellular Localisation: Secreted.

UniProt: Q14508