APCS Kit ELISA

N° du produit ABIN5510715

Détail du produit APCS Kit ELISA

Antigène: APCS (Amyloid P Component, Serum (APCS))

Épitope: AA 20-223

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human SAP/PTX2

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: E.coli
Immunogen sequence: H20-V223

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: Found in serum and urine. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: APCS (Amyloid P Component, Serum (APCS))

Autre désignation: APCS (APCS Produits)

Synonymes: PTX2 Kit ELISA, SAP Kit ELISA, Sap Kit ELISA, APCS Kit ELISA, FP Kit ELISA, SAP(FP) Kit ELISA, apcs Kit ELISA, ptx2 Kit ELISA, sap Kit ELISA, amyloid P component, serum Kit ELISA, serum amyloid P-component Kit ELISA, amyloid P component, serum protein L homeolog Kit ELISA, APCS Kit ELISA, Apcs Kit ELISA, apcs.L Kit ELISA

Sujet:

Protein Function: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.

Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened i²-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Synonyms: Serum amyloid P-component,SAP,9.5S alpha-1-glycoprotein,Serum amyloid P-component(1-203),APCS,PTX2,

Full Gene Name: Serum amyloid P-component

Cellular Localisation: Secreted.

UniProt: P02743