GDF2 Kit ELISA

N° du produit ABIN5510748

Kit ELISA Souris GDF2, test Colorimetric pour la quantification de Souris GDF2.

Aperçu rapide pour GDF2 Kit ELISA (ABIN5510748)

Antigène: GDF2 (Growth Differentiation Factor 2 (GDF2))

Épitope: AA 319-428

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit GDF2 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse BMP-9

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: CHO, Immunogen sequence: S319-R428

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: GDF2 (Growth Differentiation Factor 2 (GDF2))

Autre désignation: Gdf2

Sujet:

Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.

Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, Gdf2, Bmp9,

Full Gene Name: growth differentiation factor 2

Cellular Localisation: Secreted.

UniProt: Q9WV56

Pathways: Transition Metal Ion Homeostasis