PON1 Kit ELISA

N° du produit ABIN5510758

Ce kit ELISA Colorimetric est conçu pour la mesure quantitative de Souris PON1.

Aperçu rapide pour PON1 Kit ELISA (ABIN5510758)

Antigène: PON1 (Paraoxonase 1 (PON1))

Épitope: AA 30-355

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit PON1 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse PON1

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: E.Coli, Immunogen sequence: A30-L355

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: Plasma, liver, kidney, heart, brain, small intestine and lung. In the plasma, associated with HDL.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: PON1 (Paraoxonase 1 (PON1))

Autre désignation: Pon1

Sujet:

Protein Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.

Background: Serum paraoxonase/arylesterase 1 (PON1) also known as aromatic esterase 1 or serum aryldialkylphosphatase 1 is an enzyme that in humans is encoded by the PON1 gene. The PON gene was mapped to chromosome 7q21-q22, and the mouse Pon1 gene was mapped to the proximal end of chromosome 6. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL).

Synonyms: Serum paraoxonase/arylesterase 1, PON 1, 3.1.1.2

Full Gene Name: paraoxonase 1

Cellular Localisation: Secreted, extracellular space.

UniProt: P52430