AZGP1 Kit ELISA

N° du produit ABIN5564198

Kit ELISA Humain AZGP1, test Colorimetric pour la quantification de Humain AZGP1.

Aperçu rapide pour AZGP1 Kit ELISA (ABIN5564198)

Antigène: AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 0.9375-60 ng/mL

Application: ELISA

Type d'échantillon: Cell Culture Supernatant, Plasma, Serum

Détail du produit AZGP1 Kit ELISA

Seuil minimal de détection: 0.9375 ng/mL

Analytical Method: Quantitative

Specificité: Detects human Zinc-alpha-2-glycoprotein.

Réactivité croisée: Humain

Aucune reactivité croisée: Souris

Réactivité croisée (Details): Does not detect mouse Zinc-alpha-2-glycoprotein.

Sensibilité: 0.23 ng/mL

Attributs du produit: Zinc-alpha-2-glycoprotein (human) TurboELISA Kit
This assay is a less than 1 hour sandwich Enzyme Linked-Immunosorbent Assay (ELISA) for quantitative determination of human Zinc-alpha-2-glycoprotein in biological fluids. Zinc-alpha-2-glycoprotein (ZAG) was first identified in the 1960s, and it's name derives from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently, the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.

Information d'application

Commentaires:

TRADEMARKS - TurboELISA™ and Turbo-coated Plate™ are Trademarks of Adipogen Life Sciences.

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

Détail du antigène

Antigène: AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

Autre désignation: Zinc-alpha-2-glycoprotein

UniProt: P25311

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process