CFP Kit ELISA

N° du produit ABIN5692201

Détail du produit CFP Kit ELISA

Antigène: CFP (Complement Factor P (CFP))

Épitope: AA 28-469

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 312 pg/mL - 20000 pg/mL

Seuil minimal de détection: 312 pg/mL

Application: ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Properdin. 96wells/kit, with removable strips.

Marque: PicoKine™

Type d'échantillon: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum

Analytical Method: Quantitative

Specificité: Expression system for standard: NSO, Immunogen sequence: D28-L469

Sensibilité: < 10 pg/mL

Ingrédients: 96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
Adhesive cover

Information d'application

Durée du test: 0.5 h

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: CFP (Complement Factor P (CFP))

Autre désignation: CFP (CFP Produits)

Synonymes: BFD Kit ELISA, PFC Kit ELISA, PFD Kit ELISA, PROPERDIN Kit ELISA, BCFG Kit ELISA, Pfc Kit ELISA, Properdin Kit ELISA, complement factor properdin Kit ELISA, CFP Kit ELISA, Cfp Kit ELISA

Sujet:

Synonyms: Properdin, Complement factor P, CFP, PFC

Background: Properdin or Factor P is the only known positive regulator of complement activation that stabilizes thealternative pathway convertases. This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Cellular Localisation: Secreted.

UniProt: P27918

Pathways: Système du Complément