PF4 Kit ELISA
Aperçu rapide pour PF4 Kit ELISA (ABIN5692208)
Antigène
Voir toutes PF4 Kits ELISAÉpitope
Reactivité
Méthode de détection
Type de méthode
Gamme de detection
Application
Type d'échantillon
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Seuil minimal de détection
- 156 pg/mL
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Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat CXCL4/PF4. 96wells/kit, with removable strips.
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Marque
- PicoKine™
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Analytical Method
- Quantitative
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Specificité
- Expression system for standard: E.coli, Immunogen sequence: V30-S105
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Sensibilité
- < 15 pg/mL
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Ingrédients
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96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
Adhesive cover
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Durée du test
- 15 min
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Plaque
- Pre-coated
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Restrictions
- For Research Use only
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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Date de péremption
- 12 months
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- PF4 (Platelet Factor 4 (PF4))
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Autre désignation
- Pf4
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Sujet
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Synonyms: Platelet factor 4, PF-4, C-X-C motif chemokine 4, Pf4, Cxcl4, Scyb4
Background: Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). The PF4 gene was localized on 4q12-q13. Chemokines play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.
Cellular Localisation: Secreted. -
UniProt
- P06765
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