FSH Kit ELISA

N° du produit ABIN577075

Kit ELISA FSH Humain, Colorimetric test pour la quantification de Humain FSH.

Aperçu rapide pour FSH Kit ELISA (ABIN577075)

Antigène: FSH (Follicle-Stimulating Hormone (FSH))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit FSH Kit ELISA

Fonction: For the quantitative determination of human follicle stimulating hormone (FSH) concentrations in serum

Analytical Method: Quantitative

Sensibilité: The minimal detectable concentration of FSH by this assay is estimated to be 1.5 mIU/mL.

Ingrédients: Standards: 1 set/2 vials

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Agent conservateur: Without preservative

Détail du antigène

Antigène: FSH (Follicle-Stimulating Hormone (FSH))

Autre désignation: Follicle Stimulating Hormone (FSH)

Classe de substances: Hormone

Sujet: Epidermal growth factor (EGF), a polypeptide mitogen, was first observed in 1959 by Cohen and Levi-Montalcini while studying Nerve Growth Factor (NGF) in snake venom extracts.1 It was subsequently isolated and purified from mouse submandibular glands. When injected into new- born mice this new factor caused precocious eyelid opening and incisor eruption.2,3 EGF was further purified, based on its ability to induce the proliferation of basal skin cells.4 Also, a potent inhibitor of gastric acid secretion was identified and isolated from the urine of a pregnant women, and named human -urogastrone. It was shown that this protein was very similar to purified human EGF.5,6 The cDNA cloning of mature EGF revealed that this polypeptide (6 kDa, 53 amino acids) belonged to a family of growth factors (TGF- , vaccinia virus growth factor and amphiregulin) that bind to the same 16-185 kDa family of cell surface receptors. Structurally EGF is homologous to TGF- .7,8,9 Mature EGF is formed when the large precursor molecule (pre-EGF), a transmembrane protein (13 kDa, 1217 amino acids) which contains at least seven EGF-like sequences is cleaved. Within this precursor molecule, it is the sequence closest to the C-terminus of the mRNA that represents the coding region for the mature, soluble EGF sequence.7,1 The uncleaved precursor shows biological activity and is capable of binding to the EGF receptor.11,12 The physiological significance of the EGF precursor, nor the mechanisms of its processing into mature EGF have yet to be illustrated. However it is a source for soluble EGF and may be involved in cell to cell signalling or

Pathways: Peptide Hormone Metabolism, Chromatin Binding