SAA Kit ELISA

N° du produit ABIN577077

Ce kit ELISA Humain SAA est un kit ELISA Colorimetric conçu pour quantifier Humain SAA. Ce Kit ELISA a été cité dans 1 publication.

Aperçu rapide pour SAA Kit ELISA (ABIN577077)

Antigène: SAA (Serum Amyloid A (SAA))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit SAA Kit ELISA

Fonction: This SAA enzyme-linked immunosorbent assay (ELISA) applies a technique called quantitative sandwich immunoassay. The microtiter plate provided in this kit has been pre-coated with a monoclonal antibody specific for SAA. Standards or samples are then added to the appropriate microtiter plate wells and incubated. SAA if present, will bind and become immobilized by the antibody pre-coated on the wells. The microtiter plate wells are thoroughly washed to remove any unbound SAA and other components of sample. In order to quantitate the amount of SAA present in the sample, a standardized preparation of horseradish peroxidase (HRP)-conjugated polyclonal antibody specific for SAA is added to each well to

Analytical Method: Quantitative

Sensibilité: The minimum detectable dose of SAA was determined by adding two standard deviations to the mean optical density value of 20 zero standard replicates and calculating the corresponding concentration from the standard curve. The minimum detectable dose of human SAA using a standard curve generated with Calibrator Diluent I is 1.1 ng/mL and using Calibrator Diluent II is 0.6 ng/mL.

Ingrédients: Standards: 1 set/2 vials

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Agent conservateur: Without preservative

Références pour SAA Kit ELISA (ABIN577077)

Fu, Gibson, Simpson, McDonald: "Longitudinal changes in clinical outcomes in older patients with asthma, COPD and asthma-COPD overlap syndrome." dans: Respiration; international review of thoracic diseases, Vol. 87, Issue 1, pp. 63-74, (2014) (PubMed).

Détail du antigène

Antigène: SAA (Serum Amyloid A (SAA))

Sujet: Thyroid-stimulating hormone (TSH) is secreted by the anterior lobe of the pituitary gland and induces the production and release thyroid hormones thyroxin (T4) and triiodothryronine (T3). These thyroid hormones exert a negative feedback on the pituitary. The release of TSH is regulated by TSH-releasing hormone (TRH) produced in the hypothalamus. When there are high circulating levels of thyroid hormone in the blood, less TRH is released by the hypothalamus, so less TSH is secreted by the pituitary. The normal concentration of TSH in the blood is extremely low, but it is essential for maintenance of normal thyroid function. The determination of serum or plasma levels of TSH is recognised as a sensitive method in the diagnosis of primary and secondary hypothyroidism. Primary Congenital Hypothyroidism (CH) occurs in 1 out of every 3, to 7, infants and is caused by athyroidism and hypoplasia. If infants are screened for this disorder during their first month, then irreversible mental retardation can be prevented through early diagnosis and proper treatment. The state of infant's thyroid can be determined by a T4 and TSH combination-screening program. This is the most effective method for the clinician because secondary hypothyroidism may be missed by some TSH screenings and T4 screenings may miss minimal hyperthyroidism. Before starting therapy, a confirmation test should be performed if an infant is thought to be suffering from marginal or borderline hypothyroidism. These determinations should be performed using serum T3, T4, and TSH. Due to infant age, weight, prematurity, and demographic variation concentrations of TSH and T4 have been shown to have some variation. Thus each laboratory must establish its own normal and cut-off values. Yes Biotech Laboratories has developed a kit using a method of collecting blood spot samples on S&S #93 filter paper and ELISA techniques. This kit can quantitatively determine TSH level in neonates sensitively, accurately, safely and reliably. It is an important and practical tool to determine thyroids state of neonates, thus making it possible to prevent against infant mental retardation. S7.5(2) N-TSH