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Neuropilin 1 Kit ELISA

NRP1 Reactivité: Rat Colorimetric Sandwich ELISA 780 pg/mL - 50000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
N° du produit ABIN6720264
  • Antigène Voir toutes Neuropilin 1 (NRP1) Kits ELISA
    Neuropilin 1 (NRP1)
    Reactivité
    • 5
    • 5
    • 3
    • 1
    Rat
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Gamme de detection
    780 pg/mL - 50000 pg/mL
    Seuil minimal de détection
    780 pg/mL
    Application
    ELISA
    Fonction
    Sandwich ELISA for Quantitative Detection of Antigen
    Type d'échantillon
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    Attributs du produit

    Synonyms: A5 protein, BDCA4, BLOOD DENDRITIC CELL ANTIGEN 4, CD 304, CD304, DKFZp686A03134, DKFZp781F1414, Neuropilin-1, Neuropilin1, Neuropilin1 transmembrane receptor, NP1, NPN1, NRP 1, NRP, NRP1, NRP1_HUMAN, Vascular endothelial cell growth factor 165 receptor, VEGF165R

    Background: NRP1(Neuropilin 1) also known as NP1, NRP, BDCA4 or VEGF165R, is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF) and semaphorin family members. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion. By somatic cell hybrid analysis, the NRP1 gene was mapped to chromosome 10. NRP1 bounds PGF1 with lower affinity. NRP1-mediated interactions are a necessary element in the initiation of the primary immune response and offer another example, like that of agrin, of a molecule shared by neurologic and immunologic synapses. After T-cell contact with DC, T-cell NRP1 colocalized with CD3 in the immunologic synapse and, sometimes, also at the opposite pole of the T cell. Soluble NRP1 interacts in a homophilic fashion with NRP1 on both DC and T cells, and this binding can be inhibited by blocking antibodies to NRP1. Furthermore, selective NRP1 inhibition in this model suppressed neovascular formation substantially.

    Gene Name: NRP1

    Production: Natural and recombinant rat Neuropilin-1. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: F22-D854

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    Discover our top product NRP1 Kit ELISA
  • Indications d'application

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 50 ng/mL, 25 ng/mL, 12.5 ng/mL, 6.25 ng/mL, 3.12 ng/mL, 1.56 ng/mL, 0.78 ng/mL rat Neuropilin-1 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of rat cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. We recommend that each rat Neuropilin-1 standard solution and each sample is measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 780pg/mL-50,000pg/mL

    Volume d'échantillon
    100 μL
    Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • Antigène Voir toutes Neuropilin 1 (NRP1) Kits ELISA
    Neuropilin 1 (NRP1)
    Autre désignation
    Neuropilin-1 (NRP1 Produits)
    Synonymes
    NRP1 Kit ELISA, cd304 Kit ELISA, neuropilin Kit ELISA, np-1 Kit ELISA, npn-1 Kit ELISA, nrp Kit ELISA, nrp-1 Kit ELISA, vegf165r Kit ELISA, BDCA4 Kit ELISA, CD304 Kit ELISA, NP1 Kit ELISA, NRP Kit ELISA, VEGF165R Kit ELISA, C530029I03 Kit ELISA, NP-1 Kit ELISA, NPN-1 Kit ELISA, Npn1 Kit ELISA, Nrp Kit ELISA, neuropilin 1 Kit ELISA, neuropilin 1 L homeolog Kit ELISA, NRP1 Kit ELISA, nrp1 Kit ELISA, Nrp1 Kit ELISA, nrp1.L Kit ELISA
    ID gène
    246331
    NCBI Accession
    NP_659566
    UniProt
    Q9QWJ9
    Pathways
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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