SERPINC1 Kit ELISA
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- Antigène Voir toutes SERPINC1 Kits ELISA
- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 312 pg/mL - 20000 pg/mL
- Seuil minimal de détection
- 312 pg/mL
- Application
- ELISA
- Fonction
- Sandwich ELISA for Quantitative Detection of Antigen
- Type d'échantillon
- Cell Culture Supernatant, Plasma (EDTA - heparin - citrate), Serum, Urine
- Analytical Method
- Quantitative
- Attributs du produit
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Synonyms: ANT3_HUMAN, Antithrombin, Antithrombin III, Antithrombin-III, AntithrombinIII, AT 3, AT III, AT3, AT3D, ATIII, Heparin cofactor I, MGC22579, Serine (or cysteine) proteinase inhibitor clade C (antithrombin) member 1, Serine cysteine proteinase inhibitor clade C member 1, Serine proteinase inhibitor clade C member 1, Serpin C1, Serpin peptidase inhibitor clade C (antithrombin) member 1, SERPINC1, THPH7
Background: Antithrombin III is the most important inhibitor of thrombin and other coagulation proteinases. It belongs to the serine proteinase inhibitor (serpin) superfamily of inhibitors and structurally related proteins, which contain reactive centers that have evolved to attract and entrap certain proteinases. Inherited antithrombin III deficiency (AT3D) is a risk factor for the early development of venous thromboembolism (THPH7). Antithrombin III regulates clot formation both by inhibiting thrombin activity directly and by interfering with earlier stages of the clotting cascade. By in situ hybridization and quantitative analysis of DNA dosage in carriers of chromosome 1 deletions, AT3 is mapped to 1q23-q25. The AT3 gene has 7 exons. It contains 9 complete and 1 partial repetitive ALU sequence elements, which occur in the introns of the gene at a higher frequency (about 22 % of the intron sequence) than in the genome as a whole (about 5 %).
Gene Name: SERPINC1
Production: Natural and recombinant human Serpin C1. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: H33-K464
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- Indications d'application
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 20,000pg/mL, 10,000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL human Serpin C1 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma (heparin, EDTA, citrate) or urine to each empty well. We recommend that each human Serpin C1 standard solution and each sample is measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 312pg/mL-20,000pg/mL
- Volume d'échantillon
- 100 μL
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Antigène Voir toutes SERPINC1 Kits ELISA
- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
- Autre désignation
- Serpin C1 - Antithrombin-III (SERPINC1 Produits)
- Synonymes
- AT3 Kit ELISA, AT3D Kit ELISA, ATIII Kit ELISA, THPH7 Kit ELISA, SERPINC1 Kit ELISA, DKFZp470C1733 Kit ELISA, AI114908 Kit ELISA, At-3 Kit ELISA, At3 Kit ELISA, ANTITHROMBIN, AT-III Kit ELISA, AT-III Kit ELISA, serpin family C member 1 Kit ELISA, antithrombin-III Kit ELISA, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Kit ELISA, SERPINC1 Kit ELISA, CpipJ_CPIJ000472 Kit ELISA, CpipJ_CPIJ013111 Kit ELISA, Serpinc1 Kit ELISA
- ID gène
- 462
- NCBI Accession
- NP_000479
- UniProt
- P01008
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