CYR61 Kit ELISA

N° du produit ABIN6720366

Détail du produit CYR61 Kit ELISA

Antigène: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 31.2 pg/mL - 2000 pg/mL

Seuil minimal de détection: 31.2 pg/mL

Application: ELISA

Fonction: Sandwich ELISA for Quantitative Detection of Antigen

Type d'échantillon: Breast Milk, Cell Culture Supernatant, Plasma (EDTA - heparin), Saliva, Serum, Urine

Analytical Method: Quantitative

Attributs du produit:

Synonyms: 3CH61, CCN 1, CCN family member 1, CCN1, CCN1, CYR 61, Cyr61, CYR61 protein, CYR61 protein precursor, CYR61 protein precursor, CYR61_HUMAN, Cysteine rich angiogenic inducer 61, Cysteine rich heparin binding protein 61, Cysteine-rich angiogenic inducer 61, GIG 1, GIG1, GIG1 protein, IBP-10, IGF-binding protein 10, Igfbp 10, IGFBP-10, IGFBP10, Insulin like growth factor binding protein 10, Insulin-like growth factor-binding protein 10, Protein CYR61, Protein GIG1

Background: Cysteine-rich angiogenic inducer 61(CYR61) or CCN family member 1(CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. This gene is mapped to 1p22.3. CYR61 is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Gene Name: CYR61

Production: Natural and recombinant human CYR61. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: CHO, Immunogen sequence: A22-D381

Information d'application

Indications d'application:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL,1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human CYR61 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA), saliva, urine or human milk to each empty well. It is recommended that each human CYR61 standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 31.2pg/mL-2000pg/mL

Volume d'échantillon: 100 μL

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Détail du antigène

Antigène: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Autre désignation: CYR61 - CCN1 (CYR61 Produits)

Synonymes: CCN1 Kit ELISA, GIG1 Kit ELISA, IGFBP10 Kit ELISA, ccn1 Kit ELISA, gig1 Kit ELISA, Xcyr61 Kit ELISA, igfbp10 Kit ELISA, MGC69281 Kit ELISA, MGC69539 Kit ELISA, cyr61-l2 Kit ELISA, zgc:158158 Kit ELISA, CYR61 Kit ELISA, AI325051 Kit ELISA, Igfbp10 Kit ELISA, cysteine rich angiogenic inducer 61 Kit ELISA, cysteine-rich, angiogenic inducer, 61 Kit ELISA, cysteine-rich, angiogenic inducer, 61 like 2 Kit ELISA, cysteine rich protein 61 Kit ELISA, cysteine rich angiogenic inducer 61 S homeolog Kit ELISA, CYR61 Kit ELISA, Cyr61 Kit ELISA, cyr61 Kit ELISA, cyr61l2 Kit ELISA, cyr61.S Kit ELISA

ID gène: 3491

NCBI Accession: NP_001545

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding