HAV IgM Kit ELISA

N° du produit ABIN997031

Détail du produit HAV IgM Kit ELISA

Antigène: HAV IgM (Anti-Hepatitis A Virus Antibody IgM (HAV IgM))

Reactivité: Hepatitis A Virus (HAV)

Méthode de détection: Colorimetric

Type de méthode: Competition ELISA

Application: ELISA

Fonction: The HAV IgM ELISA test is an enzyme-linked immunosorbent assay (ELISA) which is used for the qualitative determination of IgM-class antibodies to hepatitis A virus in human serum/plasma.

Type d'échantillon: Serum

Analytical Method: Qualitative

Specificité: 100%

Sensibilité: 100%

Information d'application

Volume d'échantillon: 100 μL

Durée du test: 1 - 2 h

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Date de péremption: 12-18 months

Détail du antigène

Antigène: HAV IgM (Anti-Hepatitis A Virus Antibody IgM (HAV IgM))

Autre désignation: HAV IgM (HAV IgM Produits)

Classe de substances: Antibody

Sujet: Hepatitis A is a self-limited disease and chronic stage or other complications are rare. Infections occur early in life in areas where sanitation is poor and living conditions are crowded. With improved sanitation and hygiene, infections are delayed and consequently the number of persons susceptible to the disease increases. Because the disease is transmitted through the fecal-oral route in dense populated regions, an outbreak can arise from single contaminated source. The cause of hepatitis A is hepatitis A virus (HAV)-non enveloped positive strand RNA virus with a linear single strand genome, encoding for only one known serotype.

HAV has four major, structural polypeptides and it localizes exclusively in the cytoplasm of human hepatocytes. The infection with HAV induces strong immunological response and elevated levels first of IgM and then IgG are detectable within a few days after the onset of the symptoms. The presence of anti–HAV IgM is an important serological marker for early detection and observation of the clinical manifestation of the disease. Increasing levels of anti-HAV IgM are detectable about three weeks after exposure with highest titter after four to six weeks later. Within six months after infection IgM concentration declines to non-detectable levels.