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KLF1 Produits

(Kruppel-Like Factor 1 (erythroid) (KLF1))
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009].

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Catégories KLF1 en vedette

KLF1 Anticorps

High quality antibodies with extensive validation data.

KLF1 Kits ELISA

Reliable ELISA kits for a wide range of species.

KLF1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KLF1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, WB, IHC, FACS
Validations
  • (2)
  • (5)
N° du produit ABIN1724828
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB, IF
Validations
  • (4)
N° du produit ABIN524113
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (3)
N° du produit ABIN524111
Quantité 100 μg
Fiche technique Fiche technique

KLF1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957337
Quantité 96 tests
Fiche technique Fiche technique

KLF1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308729
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308727
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3082383
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits KLF1

Siatecka, Soni, Planutis, Bieker: "Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3)." dans: The Journal of biological chemistry, Vol. 290, Issue 15, pp. 9929-40, (2015) (PubMed).

Müller, Bauer, Siegl, Rottach, Leonhardt: "TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation." dans: Nucleic acids research, Vol. 42, Issue 13, pp. 8592-604, (2014) (PubMed).

Akgül, Lin, Ou Yang, Chen, Lu, Chen, Kikuchi, Chen, Tu: "Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis." dans: PLoS ONE, Vol. 5, Issue 12, pp. e15358, (2011) (PubMed).

Alhashem, Vinjamur, Basu, Klingmüller, Gaensler, Lloyd: "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." dans: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).

Zhou, Liu, Sun, Pawlik, Townes: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." dans: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).

Siatecka, Lohmann, Bao, Bieker: "EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation." dans: Molecular and cellular biology, Vol. 30, Issue 11, pp. 2811-22, (2010) (PubMed).

Wong, Hou, Tseng, Chien, Wu, Chen, Ho, Kyo, Teng: "Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells." dans: Stem cells (Dayton, Ohio), Vol. 28, Issue 9, pp. 1510-7, (2010) (PubMed).

Sengupta, Cohet, Morlé, Bieker: "Distinct modes of gene regulation by a cell-specific transcriptional activator." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 11, pp. 4213-8, (2009) (PubMed).

Hou, Zhao, Tanimoto, Dean: "CTCF-dependent enhancer-blocking by alternative chromatin loop formation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 51, pp. 20398-403, (2008) (PubMed).

Pandya, Townes: "Basic residues within the Kruppel zinc finger DNA binding domains are the critical nuclear localization determinants of EKLF/KLF-1." dans: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 16304-12, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à KLF1

Kruppel-like factor 1 (erythroid) (KLF-4), Kruppel like factor 1 (KLF1), Kruppel-like factor 1 (erythroid) (Klf1), Kruppel like factor 1 (Klf1), EKLF, Eklf, HBFQTL6, INLU, KLF1, Nan

Protein level used designations for KLF1

  • Kruppel-like factor 1 (erythroid)
  • Krueppel-like factor 1
  • erythroid Kruppel-like factor
  • erythroid krueppel-like transcription factor
  • erythroid-specific transcription factor EKLF
  • monoclonal antibody A3D8
  • erythroid transcription factor
  • neonatal anemia
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