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LAMC3 Protéines

(Laminin, gamma 3 (LAMC3))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 3. The gamma 3 chain is most similar to the gamma 1 chain, and contains all the 6 domains expected of the gamma chain. It is a component of laminin 12. The gamma 3 chain is broadly expressed in skin, heart, lung, and the reproductive tracts. In skin, it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration. Gamma 3 is also a prominent element of the apical surface of ciliated epithelial cells of lung, oviduct, epididymis, ductus deferens, and seminiferous tubules. The distribution of gamma 3-containing laminins along ciliated epithelial surfaces suggests that the apical laminins are important in the morphogenesis and structural stability of the ciliated processes of these cells. [provided by RefSeq, Aug 2011].

6 Résultats

LAMC3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
N° du produit ABIN7577895
 
LAMC3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
N° du produit ABIN7416799
 
LAMC3 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
N° du produit ABIN7402955
 
LAMC3 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
N° du produit ABIN7402952
 
LAMC3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2724496
 
LAMC3 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
N° du produit ABIN3010422
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • ELISA
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Réactivité
    • Human
    • Mouse
  • Images disponible
  • Carrier free only
  • Hote
    • Escherichia coli (E. coli)
    • HEK-293 Cells
  • Epitope
    • AA 1250-1418
    • AA 751-875
    • AA 901-1100
  • Conjugué
    • His tag
    • GST tag
    • His tag,GST tag
    • Myc-DYKDDDDK Tag
    • Inconjugué
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • Abbexa
    • OriGene

Pseudonymes pour LAMC3 Protéines

laminin gamma 3 (Lamc3) Protéines
laminin subunit gamma 3 (LAMC3) Protéines
AI562206 Protéines
AW240805 Protéines
OCCM Protéines
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