This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012].
custom-made
LASP1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
LASP1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
LASP1
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, ELISA, WB
custom-made
LASP1
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, ELISA, WB
Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." dans: Nature methods, Vol. 2, Issue 8, pp. 591-8, (2005) (PubMed).
Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
Gevaert, Goethals, Martens, Van Damme, Staes, Thomas, Vandekerckhove: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." dans: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, (2003) (PubMed).
Tomasetto, Régnier, Moog-Lutz, Mattei, Chenard, Lidereau, Basset, Rio: "Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17." dans: Genomics, Vol. 28, Issue 3, pp. 367-76, (1996) (PubMed).
Tomasetto, Moog-Lutz, Régnier, Schreiber, Basset, Rio: "Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains." dans: FEBS letters, Vol. 373, Issue 3, pp. 245-9, (1995) (PubMed).
Pseudonymes pour LASP1 Protéines
LIM and SH3 protein 1 (lasp1) Protéines LIM and SH3 protein 1 L homeolog (lasp1.L) Protéines LIM and SH3 protein 1 (LASP1) Protéines LIM and SH3 protein 1 (Lasp1) Protéines AA408629 Protéines Def-4 Protéines fb92f05 Protéines Lasp-1 Protéines lasp-1 Protéines lasp1 Protéines LASP1 Protéines MGC53336 Protéines MGC89667 Protéines MLN50 Protéines mln50 Protéines SH3P6 Protéines Tg(Col1a1-lacZ)1Ngma Protéines wu:fb92f05 Protéines zgc:77542 Protéines