Leptin Protéines
(Leptin (LEP))
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008].
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LEP
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
< 98 % by SDS-PAGE gel and HPLC analyses.
Active
LEP
Origine: Boeuf (Vache)
Hôte: Levure
Recombinant
> 90 %
ELISA
LEP
Origine: Takifugu rubripes
Hôte: Levure
Recombinant
> 90 %
ELISA
LEP
Origine: Cheval
Hôte: Levure
Recombinant
> 90 %
ELISA
LEP
Origine: Tetraodon nigroviridis
Hôte: Levure
Recombinant
> 90 %
ELISA
LEP
Origine: Poulet
Hôte: Levure
Recombinant
> 90 %
ELISA
LEP
Origine: Macaque rhésus
Hôte: Levure
Recombinant
> 90 %
ELISA
LEP
Origine: Chévre
Hôte: Levure
Recombinant
> 90 %
ELISA
Dernières publications pour nos Leptin Protéines
: "The effects of adipokines on cartilage and meniscus catabolism." dans: Connective tissue research, Vol. 52, Issue 6, pp. 523-33, (2012) (PubMed).: "Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues: in vitro and ex vivo studies in humans." dans: Diabetes Care, Vol. 34, Issue 1, pp. 132-8, (2011) (PubMed).
: "Effects of orexigenic peptides and leptin on melatonin secretion during different photoperiods in seasonal breeding ewes: an in vitro study." dans: Domestic animal endocrinology, Vol. 40, Issue 3, pp. 139-46, (2011) (PubMed).
: "Effect of bupivacaine on sevoflurane-induced preconditioning in isolated rat hearts." dans: European journal of pharmacology, Vol. 647, Issue 1-3, pp. 132-8, (2010) (PubMed).
: "Seasonal effects of central leptin infusion and prolactin treatment on pituitary SOCS-3 gene expression in ewes." dans: The Journal of endocrinology, Vol. 208, Issue 1, pp. 81-8, (2010) (PubMed).
: "The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system." dans: Endocrinology, Vol. 150, Issue 11, pp. 5016-26, (2009) (PubMed).
: "Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats." dans: Diabetes, Vol. 55, Issue 9, pp. 2602-10, (2006) (PubMed).
: "Leptin concentrations in maternal serum and amniotic fluid during the second trimenon: differential relation to fetal gender and maternal morphometry." dans: European journal of obstetrics, gynecology, and reproductive biology, Vol. 86, Issue 2, pp. 151-7, (1999) (PubMed).
: "Genomic structure and promoter analysis of the human obese gene." dans: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 3971-4, (1996) (PubMed).
: "Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue." dans: Diabetes, Vol. 44, Issue 7, pp. 855-8, (1995) (PubMed).
Pseudonymes pour Leptin Protéines
leptin (Lep) Protéinesleptin (LEP) Protéines
leptin (lep) Protéines
LEPD Protéines
ob Protéines
OB Protéines
obese Protéines
OBS Protéines
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