Lin-28 Homolog C (LIN28C) (N-Term) Peptide
LIN28C
Reactivité: Humain
Hôte: Synthetic
BP, IHC, WB
N° du produit ABIN979329
Aperçu rapide pour Lin-28 Homolog C (LIN28C) (N-Term) Peptide (ABIN979329)
Antigène
LIN28C
(Lin-28 Homolog C (LIN28C))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-LIN28 antibody (Catalog #: ARP34477_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LIN28C (Lin-28 Homolog C (LIN28C))
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Sujet
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LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
Alias Symbols: CSDD1, FLJ12457, LIN-28, LIN28A, ZCCHC1, LIN28, lin-28A
Protein Size: 209 -
Poids moléculaire
- 23 kDa
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ID gène
- 79727
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NCBI Accession
- NM_024674, NP_078950
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UniProt
- Q9H9Z2
Antigène
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