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LLGL2 Produits

(Lethal Giant Larvae Homolog 2 (LLGL2))

Catégories

The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories LLGL2 en vedette

LLGL2 Anticorps

High quality antibodies with extensive validation data.

LLGL2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LLGL2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
  • (4)
N° du produit ABIN561680
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (3)
N° du produit ABIN7264313
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (2)
N° du produit ABIN948088
Quantité 100 μL
Fiche technique Fiche technique

LLGL2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309482
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309484
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3093413
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits LLGL2

Dong, Zhang, Liu, Chen, Huang, Austin, Celotto, Jiang, Palladino, Jiang, Hammond, Hong: "A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia." dans: The Journal of cell biology, Vol. 211, Issue 2, pp. 273-86, (2015) (PubMed).

Patil, Bennett, Mahajan, Bronner: "Distinguishing Barrett gastric foveolar dysplasia from reactive cardiac mucosa in gastroesophageal reflux disease." dans: Human pathology, Vol. 44, Issue 6, pp. 1146-53, (2013) (PubMed).

Norman, Wisniewska, Lawrenson, Garcia-Miranda, Tada, Kajita, Mano, Ishikawa, Ikegawa, Shimada, Fujita: "Loss of Scribble causes cell competition in mammalian cells." dans: Journal of cell science, Vol. 125, Issue Pt 1, pp. 59-66, (2012) (PubMed).

Russ, Louderbough, Zarnescu, Schroeder: "Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation." dans: PLoS ONE, Vol. 7, Issue 10, pp. e47734, (2012) (PubMed).

Cong, Hirose, Harita, Yamashita, Mizuno, Hirano, Ohno: "ASPP2 regulates epithelial cell polarity through the PAR complex." dans: Current biology : CB, Vol. 20, Issue 15, pp. 1408-14, (2010) (PubMed).

Tamori, Bialucha, Tian, Kajita, Huang, Norman, Harrison, Poulton, Ivanovitch, Disch, Liu, Deng, Fujita: "Involvement of Lgl and Mahjong/VprBP in cell competition." dans: PLoS biology, Vol. 8, Issue 7, pp. e1000422, (2010) (PubMed).

Yasumi, Sakisaka, Hoshino, Kimura, Sakamoto, Yamanaka, Ohno, Takai: "Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division." dans: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6761-5, (2005) (PubMed).

Katoh, Katoh: "Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico." dans: International journal of oncology, Vol. 24, Issue 3, pp. 737-42, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à LLGL2

LLGL2, scribble cell polarity complex component L homeolog (llgl2.L), LLGL2, scribble cell polarity complex component (llgl2), lethal giant larvae homolog 2 (Drosophila) (llgl2), LLGL2, scribble cell polarity complex component (LLGL2), lethal giant larvae homolog 2 (Drosophila) (Llgl2), LLGL2, scribble cell polarity complex component (Llgl2), 9130006H11Rik, cb521, hgl, HGL, lgl-2, Lgl-2, lgl2, LGL2, llglh2, Llglh2, RGD1560307, sb:cb521, wu:fc06g08, wu:fl37c09, zgc:55895

Protein level used designations for LLGL2

  • lethal giant larvae 2
  • lethal giant larva 2
  • lethal(2) giant larvae protein homolog 2
  • pen
  • penner
  • protein penner
  • human giant larvae homolog
  • lethal giant larvae-like protein 2
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