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LOXL1 Produits

(Lysyl Oxidase-Like 1 (LOXL1))

Catégories

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008].

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Catégories LOXL1 en vedette

LOXL1 Anticorps

High quality antibodies with extensive validation data.

LOXL1 Kits ELISA

Reliable ELISA kits for a wide range of species.

LOXL1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LOXL1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7436069
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (2)
N° du produit ABIN517560
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP, IF
Validations
  • (3)
N° du produit ABIN948090
Quantité 100 μL
Fiche technique Fiche technique

LOXL1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6957602
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957603
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5593939
Quantité 96 tests
Fiche technique Fiche technique

LOXL1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3083187
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3121274
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7400942
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits LOXL1

Tjin, White, Faiz, Sicard, Tschumperlin, Mahar, Kable, Burgess: "Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis." dans: Disease models & mechanisms, Vol. 10, Issue 11, pp. 1301-1312, (2018) (PubMed).

Gayathri, Coral, Sharmila, Sripriya, Sripriya, Manish, Shantha, Ronnie, Vijaya, Narayanasamy: "Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation." dans: Current eye research, Vol. 41, Issue 10, pp. 1331-1338, (2016) (PubMed).

Aung, Ozaki, Mizoguchi, Allingham, Li, Haripriya, Nakano, Uebe, Harder, Chan, Lee, Burdon, Astakhov, Abu-Amero, Zenteno, Nilgün, Zarnowski, Pakravan, Safieh, Jia, Wang, Williams, Paoli, Schlottmann et al.: "A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. ..." dans: Nature genetics, Vol. 47, Issue 4, pp. 387-92, (2015) (PubMed).

Coral, Madhavan, Pukhraj, Angayarkanni: "High glucose induced differential expression of lysyl oxidase and its isoform in ARPE-19 cells." dans: Current eye research, Vol. 38, Issue 1, pp. 194-203, (2013) (PubMed).

Sethi, Wordinger, Clark: "Gremlin utilizes canonical and non-canonical TGF? signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells." dans: Experimental eye research, Vol. 113, pp. 117-27, (2013) (PubMed).

Schlötzer-Schrehardt, Hammer, Krysta, Hofmann-Rummelt, Pasutto, Sasaki, Kruse, Zenkel: "LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma." dans: Ophthalmology, Vol. 119, Issue 9, pp. 1832-43, (2012) (PubMed).

Ohmura, Yasukawa, Minami, Sugi, Oba, Nagata, Kyogoku, Ohshima, Aoki, Imaizumi: "Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice." dans: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 35, Issue 11, pp. 1063-8, (2012) (PubMed).

Sethi, Mao, Wordinger, Clark: "Transforming growth factor-beta induces extracellular matrix protein cross-linking lysyl oxidase (LOX) genes in human trabecular meshwork cells." dans: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5240-50, (2011) (PubMed).

Trackman: "Diverse biological functions of extracellular collagen processing enzymes." dans: Journal of cellular biochemistry, Vol. 96, Issue 5, pp. 927-37, (2005) (PubMed).

Mki, Sormunen, Lippo, Kaarteenaho-Wiik, Soininen, Myllyharju: "Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues." dans: The American journal of pathology, Vol. 167, Issue 4, pp. 927-36, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à LOXL1

lysyl oxidase like 1 (LOXL1), lysyl oxidase like 1 (loxl1), lysyl oxidase-like 1 (Loxl1), lysyl oxidase-like 1 (loxl1), lysyl oxidase like 1 L homeolog (loxl1.L), LOL, lol, LOXL, Loxl, loxl, loxl-1, oxl-1, si:ch211-238c15.1

Protein level used designations for LOXL1

  • lysyl oxidase-like 1
  • lysyl oxidase homolog 1-like
  • lysyl oxidase homolog 1
  • lysyl oxidase-like protein 1
  • lysyl oxidase 2
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