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LYN Produits

(V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Catégories

This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].

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Catégories LYN en vedette

LYN Anticorps

High quality antibodies with extensive validation data.

LYN Kits ELISA

Reliable ELISA kits for a wide range of species.

LYN Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LYN recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
  • (8)
N° du produit ABIN6256754
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (4)
N° du produit ABIN392102
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP, IHC (p), IF, ICC
Validations
  • (4)
N° du produit ABIN2854977
Quantité 100 μL
Fiche technique Fiche technique

LYN recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960426
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN4886186
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380125
Quantité 2 x 96 tests
Fiche technique Fiche technique

LYN recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5570567
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125686
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309925
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits LYN

Kuai, Luo, Qu, Ru, Luo, Ding, Xing, Liu, Sun, Li, Li: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." dans: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).

Iriyama, Yuan, Hatta, Takagi, Takei et al.: "Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and ..." dans: Cancer cell international, Vol. 16, pp. 37, (2016) (PubMed).

Hu, Takano, Xiang, Gilkes, Luo, Semenza: "Hypoxia-inducible factors enhance glutamate signaling in cancer cells." dans: Oncotarget, Vol. 5, Issue 19, pp. 8853-68, (2014) (PubMed).

Kiflemariam, Andersson, Asplund, Pontén, Sjöblom: "Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers." dans: PLoS ONE, Vol. 7, Issue 3, pp. e32927, (2012) (PubMed).

Queval, Nicolas, Beau: "Role of Src kinases in mobilization of glycosylphosphatidylinositol-anchored decay-accelerating factor by Dr fimbria-positive adhering bacteria." dans: Infection and immunity, Vol. 79, Issue 7, pp. 2519-34, (2011) (PubMed).

Okamoto, Hayakawa, Miyata, Watamoto, Emi, Abe, Kiyoi, Towatari, Naoe: "Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD." dans: Leukemia, Vol. 21, Issue 3, pp. 403-10, (2007) (PubMed).

Baran, Tridandapani, Helgason, Humphries, Krystal, Marsh: "The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity." dans: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38628-36, (2003) (PubMed).

Donato, Wu, Stapley, Gallick, Lin, Arlinghaus, Talpaz: "BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571." dans: Blood, Vol. 101, Issue 2, pp. 690-8, (2003) (PubMed).

Liang, Wisniewski, Strife, Shivakrupa, Clarkson, Resh: "Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling." dans: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13732-8, (2002) (PubMed).

Santini, Scappini, Grossi, Gozzini, Bonsi, Pagliai, Rossi Ferrini, Bagnara: "Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647." dans: Haematologica, Vol. 87, Issue 12, pp. 1242-7, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à LYN

LYN proto-oncogene, Src family tyrosine kinase (LYN), v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (lyn), LYN proto-oncogene, Src family tyrosine kinase (Lyn), tyrosine-protein kinase Lyn (LOC100593961), LYN proto-oncogene, Src family tyrosine kinase L homeolog (lyn.L), LYN proto-oncogene, Src family tyrosine kinase (lyn), AA407514, CH73-38P6.3, Hck-2, JTK8, jtk8, lyn, LYN, lyn-A, p53Lyn, p56Lyn, zgc:92124

Protein level used designations for LYN

  • lck/Yes-related novel protein tyrosine kinase
  • tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Lyn
  • lyn protein tyrosine kinase
  • lyn protein non-receptor kinase
  • v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
  • v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein
  • V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
  • Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
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