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EDG-4

LPAR2 PC Whole Cell Lysate
N° du produit ABIN924991
600,00 €
Plus frais de livraison 40,00 € et TVA
100 μL
Destination: France
Envoi sous 15 à 22 jours ouvrables

Aperçu rapide pour EDG-4 (ABIN924991)

Antigène

EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))

Application

Positive Control (PC)

Lysate Fraction

Whole Cell Lysate
  • Indications d'application

    For use as a positive control with EDG-4 monoclonal antibodies catalog numbers MC-914 and MC-915. Use 10-20 µl of EDG-4 cell lysate per lane as a control for using EDG-4 antibody.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Cell lysate provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol.

    Stock

    -20 °C
  • Antigène

    EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))

    Autre désignation

    EDG-4

    Sujet

    EDG-4 Transfected Cell Positive Control Lysate. EDG-4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-4 is lysophospholipid. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG-4 is expressed in testes, ovarian tumor and leukocyte containing tissues.
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