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MBD2 Protéines

(Methyl-CpG Binding Domain Protein 2 (MBD2))

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].

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MBD2 Protein (AA 1-414) (His tag)

custom-made MBD2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Mbd2 Protein, UniprotID Q9Z2E1

3 images

N° du produit ABIN7556423

Détails

MBD2 Protein (AA 1-411) (His tag)

custom-made MBD2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant MBD2 Protein, UniprotID Q9UBB5

3 images

N° du produit ABIN7549234

Détails

MBD2 Protein (AA 145-411) (His tag)

MBD2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

N° du produit ABIN7417450

Détails

MBD2 Protein (AA 1-414) (Strep Tag)

custom-made MBD2 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3120369

Détails

MBD2 Protein (AA 1-411) (Strep Tag)

custom-made MBD2 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3083393