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MEF2D Produits

(Myocyte Enhancer Factor 2D (MEF2D))

Catégories

This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

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Catégories MEF2D en vedette

MEF2D Anticorps

High quality antibodies with extensive validation data.

MEF2D Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MEF2D recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7160506
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN517838
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
N° du produit ABIN517841
Quantité 100 μg
Fiche technique Fiche technique

MEF2D recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648635
Quantité 96 tests
Fiche technique Fiche technique

MEF2D recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124047
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310694
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310696
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MEF2D

Okamoto, Li, Ju, Scholzke, Mathews, Cui, Salvesen, Bossy-Wetzel, Lipton: "Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 6, pp. 3974-9, (2002) (PubMed).

Guttridge, Mayo, Madrid, Wang, Baldwin: "NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia." dans: Science (New York, N.Y.), Vol. 289, Issue 5488, pp. 2363-6, (2000) (PubMed).

Mora, Pessin: "The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive GLUT4 glucose transporter." dans: The Journal of biological chemistry, Vol. 275, Issue 21, pp. 16323-8, (2000) (PubMed).

Kato, Zhao, Morikawa, Sugiyama, Chakravortty, Koide, Yoshida, Tapping, Yang, Yokochi, Lee: "Big mitogen-activated kinase regulates multiple members of the MEF2 protein family." dans: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18534-40, (2000) (PubMed).

Zhao, New, Kravchenko, Kato, Gram, di Padova, Olson, Ulevitch, Han: "Regulation of the MEF2 family of transcription factors by p38." dans: Molecular and cellular biology, Vol. 19, Issue 1, pp. 21-30, (1999) (PubMed).

Breitbart, Liang, Smoot, Laheru, Mahdavi, Nadal-Ginard: "A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage." dans: Development (Cambridge, England), Vol. 118, Issue 4, pp. 1095-106, (1994) (PubMed).

Martin, Miano, Hustad, Copeland, Jenkins, Olson: "A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing." dans: Molecular and cellular biology, Vol. 14, Issue 3, pp. 1647-56, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à MEF2D

myocyte enhancer factor 2D (mef2d), myocyte enhancer factor 2D (MEF2D), MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) (MEF2D), myocyte enhancer factor 2D (Mef2d), C80750, MGC145245, sl-1, sl1, XMEF2D

Protein level used designations for MEF2D

  • myocyte enhancer factor 2D
  • MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)
  • myocyte-specific enhancer factor 2D-like
  • MADS box transcription enhancer factor 2, polypeptide D
  • myocyte-specific enhancer factor 2D
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