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MFN2 Produits

(Mitofusin 2 (MFN2))
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].

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Catégories MFN2 en vedette

MFN2 Anticorps

High quality antibodies with extensive validation data.

MFN2 Kits ELISA

Reliable ELISA kits for a wide range of species.

MFN2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MFN2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), RNAi
Validations
  • (8)
  • (7)
N° du produit ABIN564263
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rabbit, Rat
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (2)
  • (5)
N° du produit ABIN682528
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN6143800
Quantité 100 μL
Fiche technique Fiche technique

MFN2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6968636
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957855
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1142903
Quantité 96 tests
Fiche technique Fiche technique

MFN2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310805
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3083597
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3124269
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MFN2

Mandik, Kanana, Rody, Misera, Wilken, Laabs von Holt, Klein, Vos: "A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities." dans: Frontiers in cell and developmental biology, Vol. 10, pp. 1000553, (2022) (PubMed).

Aydogan Mathyk, Temel Yuksel, Tayyar, Aslan Cetin, Tayyar, Koroglu: "Maternal serum mitofusin-2 levels in patients with preeclampsia: the possible role of mitochondrial dysfunction in preeclampsia." dans: The journal of maternal-fetal & neonatal medicine, pp. 1-6, (2019) (PubMed).

Meng, Liu, Liu, Song, Liu, Xie, Han, Ji: "Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3-dependent manner." dans: British journal of pharmacology, Vol. 175, Issue 8, pp. 1126-1145, (2018) (PubMed).

Zhou, Zhang, He, Zhuang, Han, Jiang, Yao, Huang, Ling, Lin, Lin: "Downregulation of mitochondrial cyclooxygenase-2 inhibits the stemness of nasopharyngeal carcinoma by decreasing the activity of dynamin-related protein 1." dans: Theranostics, Vol. 7, Issue 5, pp. 1389-1406, (2018) (PubMed).

Li, Chen, Sun, Pang: "Enhancement of Mitochondrial Transfer by Antioxidants in Human Mesenchymal Stem Cells." dans: Oxidative medicine and cellular longevity, Vol. 2017, pp. 8510805, (2018) (PubMed).

Hui, Lu, Han, Zhou, Liu, Li, Jin: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." dans: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).

Yamauchi, Yamamura, Katase, Itadani, Okada, Kobiki, Nakamura, Yamaguchi, Kuribayashi: "Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device." dans: BMC cancer, Vol. 17, Issue 1, pp. 234, (2017) (PubMed).

Ku, Ji, Zhang, Li, Sang: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." dans: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).

Siu, Zhou, Yu, Zhang, Wang, Liang, Chen, Chan, Yu: "Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation." dans: Scientific reports, Vol. 6, pp. 23464, (2016) (PubMed).

Chen, Chen, Wang, Tan, Zhu, Li, Han, Chen, Gao, Liu, Chen: "Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." dans: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à MFN2

mitofusin 2 (MFN2), Mitochondrial assembly regulatory factor (Marf), mitofusin 2 (mfn2), mitofusin-2 (LOC100186475), mitofusin 2 (Mfn2), mitofusin 2 L homeolog (mfn2.L), anon-WO0125274.3, CG3869, cmt2a, CMT2A, cmt2a2, CMT2A2, cprp1, CPRP1, D630023P19Rik, Dmel\\CG3869, dMFN, dMfn, dmfn, Fzo, hsg, HSG, MARF, marf, Marf-1, Mfn, mfn, mfn2, MFN2, mg:cb01g09, si:dkeyp-104h9.2, wu:fb79a11

Protein level used designations for MFN2

  • CG3869-PA
  • CG3869-PB
  • CG3869-PC
  • Marf-PA
  • Marf-PB
  • Marf-PC
  • drosophila mitofusin
  • mitochondrial assembly regulatory factor
  • mitofusin
  • mitofusin 2
  • mitofusin-2
  • mitofusin-2-like
  • hyperplasia suppressor
  • transmembrane GTPase MFN2
  • HSG protein
  • hypertension related protein 1
  • hypertension-related protein 1
  • hypertension-related protein
  • mitochondrial transmembrane GTPase FZO1A
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