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Minichromosome Maintenance Complex Component 3 Produits

(Minichromosome Maintenance Complex Component 3 (MCM3))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].

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Catégories Minichromosome Maintenance Complex Component 3 en vedette

Minichromosome Maintenance Complex Component 3 Anticorps

High quality antibodies with extensive validation data.

Minichromosome Maintenance Complex Component 3 Kits ELISA

Reliable ELISA kits for a wide range of species.

Minichromosome Maintenance Complex Component 3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Minichromosome Maintenance Complex Component 3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (11)
N° du produit ABIN561761
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (7)
N° du produit ABIN3021327
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
N° du produit ABIN7268540
Quantité 100 μL
Fiche technique Fiche technique

Minichromosome Maintenance Complex Component 3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957841
Quantité 96 tests
Fiche technique Fiche technique

Minichromosome Maintenance Complex Component 3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1310549
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093723
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3133430
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Minichromosome Maintenance Complex Component 3

Gelhaus, Gilad, Hwang, Penning, Blair: "Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells." dans: Toxicology letters, Vol. 209, Issue 1, pp. 58-66, (2012) (PubMed).

Nodin, Fridberg, Jonsson, Bergman, Uhlén, Jirström: "High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanoma." dans: Diagnostic pathology, Vol. 7, pp. 82, (2012) (PubMed).

Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." dans: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).

Hubbi, Luo, Baek, Semenza: "MCM proteins are negative regulators of hypoxia-inducible factor 1." dans: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).

Ehlén, Nodin, Rexhepaj, Brändstedt, Uhlén, Alvarado-Kristensson, Pontén, Brennan, Jirström: "RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer." dans: Translational oncology, Vol. 4, Issue 4, pp. 212-21, (2011) (PubMed).

Liu, Vaithiyalingam, Shi, Chazin, Zinkel: "BID binds to replication protein A and stimulates ATR function following replicative stress." dans: Molecular and cellular biology, Vol. 31, Issue 21, pp. 4298-309, (2011) (PubMed).

Kim, Kee, Gurtan, DAndrea: "Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24." dans: Blood, Vol. 111, Issue 10, pp. 5215-22, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à Minichromosome Maintenance Complex Component 3

minichromosome maintenance complex component 3 (MCM3), MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) (mcm3), minichromosome maintenance complex component 3 (mcm3), minichromosome maintenance complex component 3 (Mcm3), Minichromosome maintenance 3 (Mcm3), minichromosome maintenance complex component 3 L homeolog (mcm3.L), MCM complex subunit Mcm3 (mcm3), AL033361, C80350, cb32, CG4206, chunp6867, dMCM3, Dmel\\CG4206, DmeMCM3, DmMCM3, DmMcm3, HCC5, MCM3, McM3, Mcmd, Mcp-PCR2, P1, P1-MCM3, P1.h, p1.m, PCR2, RLFB, wu:fa26g03, xmcm3

Protein level used designations for Minichromosome Maintenance Complex Component 3

  • DNA polymerase alpha holoenzyme-associated protein P1
  • DNA replication factor MCM3
  • DNA replication licensing factor MCM3
  • MCM3 minichromosome maintenance deficient 3
  • RLF subunit beta
  • cervical cancer proto-oncogene 5
  • hRlf beta subunit
  • minichromosome maintenance deficient 3
  • p102
  • replication licensing factor, beta subunit
  • zMCM3
  • zygotic DNA replication licensing factor mcm3
  • zygotic minichromosome maintenance protein 3
  • P1-MCM3
  • mini chromosome maintenance deficient
  • CG4206-PA
  • Mcm3-PA
  • minichromosome maintenance 3
  • minichromosome maintenance-PCR2
  • P1 homolog
  • XRLF subunit beta
  • mMCM3
  • maternal DNA replication licensing factor mcm3
  • maternal minichromosome maintenance protein 3
  • p100
  • Minichromosome maintenance protein 3
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