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Mitogen-Activated Protein Kinase Kinase Kinase 3 Protéines

(Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))

This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively\; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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MAP3K3 Protein (AA 1-626) (His tag)

custom-made MAP3K3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant MAP3K3 Protein, UniprotID Q99759

3 images

N° du produit ABIN7549217

Détails

MAP3K3 Protein (AA 1-626) (His tag)

custom-made MAP3K3 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Map3k3 Protein, UniprotID Q61084

3 images

N° du produit ABIN7557662

Détails

MAP3K3 Protein (AA 1-90) (GST tag)

MAP3K3 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 1-90) protein (GST tag) (ABIN1310214)

1 image

N° du produit ABIN1310214

Détails

MAP3K3 Protein (GST tag)

MAP3K3 Origine: Humain Hôte: Cellules d'insectes Recombinant 70 % - 90 % Func Active

N° du produit ABIN5509009

Détails

MAP3K3 Protein (AA 1-626) (Strep Tag)

custom-made MAP3K3 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, ELISA, WB

N° du produit ABIN3122846

Détails

MAP3K3 Protein (AA 1-626) (Strep Tag)

custom-made MAP3K3 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, ELISA, WB

N° du produit ABIN3083367